Description

Chmfl-Pi3Kd-317 is a potent and selective small molecule inhibitor targeting the delta isoform of phosphoinositide 3-kinase (PI3Kδ). This compound is a critical research tool for investigating the PI3Kδ signaling pathway, which plays a pivotal role in B-cell activation, proliferation, and survival. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on oncology, immunology, and inflammatory disease research.

Application

• Biochemical Research: Used as a selective probe to study the specific biological functions and signaling mechanisms of the PI3Kδ isoform in cellular models.
• Drug Discovery & Development: Serves as a reference compound or lead molecule in high-throughput screening and structure-activity relationship (SAR) studies for novel PI3Kδ inhibitors.
• Oncology Research: Investigated for its potential therapeutic effects in hematological malignancies, such as chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma, where PI3Kδ is often dysregulated.
• Immunology & Inflammation Studies: Applied in research focused on autoimmune diseases and allergic responses, where PI3Kδ inhibition can modulate immune cell function.
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate pharmacokinetics, pharmacodynamics, and efficacy profiles.

Basic Information

Product Name	Chmfl-Pi3Kd-317
CAS No.	2244992-76-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PI3Kδ Inhibitor Chmfl-Pi3Kd-317; Chmfl Pi3Kd 317; Chmfl-Pi3Kd317; 2244992-76-3; Phosphoinositide 3-kinase delta inhibitor; PI3K-delta inhibitor Chmfl-Pi3Kd-317
EINECS	Contact for details

Quality Control

Our Chmfl-Pi3Kd-317 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques, including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation. The material is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.