Description

Bi-4916 CAS NO 2244451-48-5 is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a reliable building block for complex molecular architectures. It is primarily utilized by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery programs targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for clinical development.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Bioconjugation: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Proteolysis-Targeting Chimera (PROTAC) Development: Employed as a component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Integral for creating tool compounds to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Supports the transition from laboratory-scale synthesis to pilot and commercial manufacturing processes.

Basic Information

Product Name	Bi-4916
CAS No.	2244451-48-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BI-4916; 2244451-48-5; BI 4916; Bi4916; (S)-BI-4916; BI-4916 (S-enantiomer); (S)-enantiomer of BI-4916; 1H-Pyrrolo[2,3-b]pyridine-5-carboxamide, N-[(3S)-1-(2-fluorophenyl)-1,2-dihydro-3H-pyrrolo[3,2-c]pyridin-3-yl]-2-methyl-
EINECS	Contact for details

Quality Control

Every batch of Bi-4916 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our quality control protocols are designed to meet the stringent requirements of pharmaceutical R&D and pre-clinical manufacturing. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and MS analyses, is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.