Description

Cxcr7 Modulator 1 is a potent and selective small molecule inhibitor of the C-X-C chemokine receptor type 7 (CXCR7), also known as ACKR3. This compound is of significant interest for its role in modulating key biological pathways involved in cell migration, immune response, and tumor microenvironment interactions. It is primarily utilized by researchers and pharmaceutical developers in oncology, immunology, and cardiovascular disease research for target validation, mechanism of action studies, and as a lead compound in drug discovery programs.

Application

• Biomedical Research: Used as a critical pharmacological tool to study the role of CXCR7/ACKR3 in cancer progression, metastasis, and angiogenesis.
• Drug Discovery & Development: Serves as a reference compound or lead molecule for developing novel therapeutics targeting inflammatory diseases and certain cancers.
• Cell Signaling Studies: Applied in in vitro and in vivo models to elucidate signaling pathways involving β-arrestin recruitment and receptor internalization.
• Immunology Research: Investigated for its effects on immune cell trafficking and the modulation of chemokine gradients in autoimmune and inflammatory conditions.
• Academic & Contract Research: Supplied to universities, research institutes, and CROs for basic science and preclinical studies.

Basic Information

Product Name	Cxcr7 Modulator 1
CAS No.	2231812-31-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CXCR7 Inhibitor; ACKR3 Modulator; CXCR7/ACKR3 antagonist; (R)-N-(1-(3,4-Dichlorophenyl)ethyl)-5-methyl-1H-pyrazolo[3,4-b]pyridin-4-amine; 2231812-31-8; CCR7 Modulator (context-dependent); Chemokine receptor modulator 1
EINECS	Contact for details

Quality Control

Our Cxcr7 Modulator 1 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR/MS), and impurity profiles are available for every lot. We adhere to high standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.