Description

Flt3-In-3 CAS NO 2229050-90-0 is a potent and selective small molecule inhibitor targeting the FMS-like tyrosine kinase 3 (FLT3) receptor. This compound is of significant value in pharmaceutical research and development, particularly for investigating novel therapeutic strategies in oncology. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical developers focused on hematologic malignancies, cancer biology, and kinase signaling pathways.

Application

• Biochemical Research: Used as a critical tool compound for studying FLT3 kinase activity, signal transduction, and downstream effects in cellular models.
• Oncology Drug Discovery: Serves as a reference standard or lead compound in the development of novel FLT3-targeted therapies for acute myeloid leukemia (AML) and other cancers.
• Cellular Assay Development: Employed in high-throughput screening (HTS) and functional assays to validate FLT3-dependent cellular processes and mechanisms of action.
• Preclinical Studies: Utilized in in vitro and in vivo models to evaluate the efficacy, pharmacokinetics, and pharmacodynamics of FLT3 inhibition.
• Mechanism of Action Studies: Applied to investigate drug resistance mechanisms and combination therapy strategies involving FLT3 pathway inhibition.

Basic Information

Product Name	Flt3-In-3
CAS No.	2229050-90-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Flt3-In-3; FLT3 Inhibitor 3; 2229050-90-0; FLT3-IN-3; FLT3 inhibitor compound 3; FMS-like tyrosine kinase 3 inhibitor 3
EINECS	Contact for details

Quality Control

Our Flt3-In-3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research use. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a desiccator to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.