Description

Egfr-In-5 is a potent and selective small-molecule inhibitor of the Epidermal Growth Factor Receptor (EGFR), a key target in oncology and cell signaling research. This high-purity compound is essential for researchers developing novel therapeutic strategies and investigating signaling pathways associated with cancer proliferation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on kinase inhibitor discovery and preclinical studies.

Application

• Biochemical Research: Used as a selective tool compound for studying EGFR-mediated signal transduction pathways in vitro.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in the development of novel anti-cancer therapeutics targeting EGFR mutations.
• Cellular Assays: Employed to inhibit EGFR activity in cell-based models to study effects on proliferation, apoptosis, and migration.
• Kinase Profiling: A critical reagent for selectivity screening against panels of kinases to assess off-target effects.
• Preclinical Studies: Utilized in animal models to evaluate the pharmacokinetics, efficacy, and safety profiles of EGFR-targeting agents.

Basic Information

Product Name	Egfr-In-5
CAS No.	2225887-26-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	EGFR-IN-5; EGFR Inhibitor 5; 2225887-26-1; Epidermal Growth Factor Receptor Inhibitor 5; N-[3-[[5-Chloro-2-[(1-methyl-4-piperidinyl)oxy]phenyl]amino]quinoxalin-2-yl]-4-(dimethylamino)butanamide (IUPAC); Egfr Inhibitor-5; EGFR Tyrosine Kinase Inhibitor 5
EINECS	Contact for details

Quality Control

Our Egfr-In-5 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert conditions for long-term stability. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.