Description

2-Fluoro-6-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-couplings for synthesizing fluorinated and methoxy-substituted pyridine cores found in drug candidates.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Ligand and Catalyst Development: Used to prepare specialized ligands for transition metal catalysts in asymmetric synthesis.
• Materials Science Research: Intermediate in the synthesis of organic electronic materials, such as OLED emitters and charge-transport layers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and target engagement.
• Custom Synthesis and R&D: Serves as a versatile starting material for contract research organizations and academic laboratories.

Basic Information

Product Name	2-Fluoro-6-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	2223043-31-8
Molecular Formula	C₁₃H₁₉BFNO₃
Molecular Weight	267.11 g/mol
Synonyms	2-Fluoro-6-methoxypyridine-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluoro-6-methoxypyridine; 2-Fluoro-6-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Fluoro-6-methoxy-4-pyridineboronic acid pinacol ester; 4-Borono-2-fluoro-6-methoxypyridine pinacol ester; (2-Fluoro-6-methoxypyridin-4-yl)boronic acid pinacol ester; PINACOL 2-FLUORO-6-METHOXYPYRIDINE-4-BORONATE
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.