Description

(2-(Difluoromethoxy)Pyridin-3-Yl)Methanol is a high-purity pyridine derivative featuring a difluoromethoxy substituent, a key structural motif in modern medicinal chemistry. This compound serves as a versatile and critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated heterocycles into their molecular designs.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where fluorination enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals with unique electronic and surface properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biological molecules for metabolic pathway studies and imaging applications.

Basic Information

Product Name	(2-(Difluoromethoxy)Pyridin-3-Yl)Methanol
CAS No.	2222104-49-4
Molecular Formula	C7H7F2NO2
Molecular Weight	175.13 g/mol
Synonyms	3-(Hydroxymethyl)-2-(difluoromethoxy)pyridine; 2-(Difluoromethoxy)-3-pyridinemethanol; (2-(Difluoromethoxy)-3-pyridyl)methanol; 3-Pyridinemethanol, 2-(difluoromethoxy)-; (2-Difluoromethoxypyridin-3-yl)methanol; DFMP Alcohol; DFM-Pyridine Methanol
EINECS	Contact for details

Quality Control

Every batch of (2-(Difluoromethoxy)Pyridin-3-Yl)Methanol is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to guarantee identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.