Description

Pdgfrα Kinase Inhibitor 1 is a potent and selective small molecule inhibitor targeting the Platelet-Derived Growth Factor Receptor Alpha (PDGFRα) kinase. This compound is a critical research tool for investigating cellular signaling pathways, cancer biology, and the role of PDGFRα in fibrosis and other proliferative diseases. It is essential for pharmaceutical R&D, academic research, and biotechnology companies focused on oncology and targeted therapy development. The product is supplied as a high-purity biochemical reagent for research use.

Application

• Biochemical Research: Used as a selective inhibitor to study PDGFRα signaling pathways and downstream effects in cell-based assays.
• Oncology Research: A key tool for investigating the role of PDGFRα in tumor growth, angiogenesis, and metastasis in various cancer models.
• Drug Discovery & Development: Serves as a reference compound or lead molecule in high-throughput screening and structure-activity relationship (SAR) studies for kinase inhibitor programs.
• Fibrosis Research: Applied in studies exploring the inhibition of PDGFRα in fibrotic diseases affecting the liver, lungs, and other organs.
• Cellular Mechanism Studies: Utilized to elucidate the function of PDGFRα in cell proliferation, differentiation, and migration.
• In Vitro Diagnostics Development: May be used in the development of assay kits and diagnostic platforms targeting kinase activity.

Basic Information

Product Name	Pdgfrα Kinase Inhibitor 1
CAS No.	2209053-93-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PDGFRα Inhibitor 1; PDGFR-alpha Kinase Inhibitor; PDGFRA Kinase Inhibitor; 2209053-93-8; PDGFRα Inhibitor; Platelet-derived growth factor receptor alpha inhibitor; Research compound 2209053-93-8
EINECS	Contact for details

Quality Control

Our Pdgfrα Kinase Inhibitor 1 is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is analyzed using advanced chromatographic and spectroscopic methods, including HPLC and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. The container should be kept in a dry, cool environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.