Description

Fzd4 Agonist Fzm1.8) CAS NO 2204290-85-5 is a potent and selective small molecule agonist designed to target and activate the Frizzled-4 (Fzd4) receptor, a key component in the Wnt signaling pathway. This compound is of significant value for research and development in the fields of vascular biology, tissue regeneration, and oncology, where precise modulation of Wnt/β-catenin signaling is critical. It is an essential tool for pharmaceutical companies, biotechnology research institutes, and academic laboratories engaged in high-throughput screening, target validation, and the development of novel therapeutics for diseases involving angiogenesis and cell proliferation.

Application

• Pharmaceutical R&D: Used as a lead compound or reference standard in the discovery and development of novel therapeutics targeting the Wnt signaling pathway.
• Biochemical Research: Serves as a critical tool for studying the role of Frizzled-4 receptors in cellular processes, including angiogenesis, tissue repair, and stem cell regulation.
• High-Throughput Screening (HTS): Employed in assay development and screening campaigns to identify and characterize new modulators of Wnt/β-catenin signaling.
• Academic & Preclinical Studies: Facilitates in vitro and in vivo research into diseases such as retinopathies, cancers, and disorders of vascular development.
• Cell Culture & Differentiation: Applied in studies to direct stem cell fate and promote specific tissue regeneration by activating Fzd4-mediated signaling cascades.

Basic Information

Product Name	Fzd4 Agonist Fzm1.8) CAS NO 2204290-85-5
CAS No.	2204290-85-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FZD4 Agonist FZM-1.8; FZM 1.8; Frizzled-4 Receptor Agonist Fzm1.8; Fzd4 Agonist; CAS 2204290-85-5; Wnt pathway activator Fzm1.8; FZM1.8 compound
EINECS	Contact for details

Quality Control

Every batch of our Fzd4 Agonist Fzm1.8 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and potency. We adhere to high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for assay, purity (by HPLC), and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Assay	95.0% - 105.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.