Description

1-[2-Methyl-3-(Trifluoromethyl)Phenyl]-1H-Pyrrole-2-Carbaldehyde is a high-value, multi-functional heterocyclic building block featuring a pyrrole core substituted with a trifluoromethylphenyl group. This compound matters for its unique structural motifs, which are critical for modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, material science, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated pyrrole-aldehyde system.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable scaffold for introducing fluorine atoms into complex molecules, leveraging the properties of the trifluoromethyl group to improve metabolic stability and lipophilicity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	1-[2-Methyl-3-(Trifluoromethyl)Phenyl]-1H-Pyrrole-2-Carbaldehyde
CAS No.	2197063-05-9
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	1H-Pyrrole-2-carboxaldehyde, 1-[2-methyl-3-(trifluoromethyl)phenyl]-; 2-Formyl-1-[2-methyl-3-(trifluoromethyl)phenyl]pyrrole; 1-(2-Methyl-3-trifluoromethylphenyl)pyrrole-2-carbaldehyde; N-[2-Methyl-3-(trifluoromethyl)phenyl]pyrrole-2-carboxaldehyde; 2197063-05-9; Pyrrole-2-carbaldehyde derivative with trifluoromethylphenyl group
EINECS	Contact for details

Quality Control

Our 1-[2-Methyl-3-(Trifluoromethyl)Phenyl]-1H-Pyrrole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.