Description

Bcl-2/Bcl-Xl Inhibitor 1 CAS NO 2180923-05-9 is a potent, small-molecule inhibitor designed to selectively target and disrupt the anti-apoptotic functions of Bcl-2 and Bcl-XL proteins. This compound is critical for advancing research into programmed cell death mechanisms and developing novel therapeutic strategies for oncology and other diseases characterized by apoptotic dysregulation. It is an essential research-grade biochemical for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on cancer biology, drug discovery, and preclinical studies.

Application

• Cancer Research & Drug Discovery: A key tool compound for studying apoptosis pathways and validating Bcl-2/Bcl-XL as therapeutic targets in various cancer models.
• Biochemical Assay Development: Used as a reference standard and positive control in high-throughput screening (HTS) campaigns and functional assays to identify novel apoptosis modulators.
• Mechanistic Studies: Enables detailed investigation of protein-protein interactions within the Bcl-2 family and their role in cell survival and death.
• Preclinical Pharmacology: Supports in vitro and in vivo efficacy and toxicity studies for potential oncology therapeutics.
• Academic Research: Facilitates fundamental biological research into apoptosis, cellular stress responses, and related disease mechanisms.
• Combination Therapy Studies: Used to explore synergistic effects with other chemotherapeutic agents or targeted therapies.

Basic Information

Product Name	Bcl-2/Bcl-Xl Inhibitor 1
CAS No.	2180923-05-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bcl-2/Bcl-xL inhibitor 1; Bcl-2/Bcl-XL Inhibitor; Apoptosis Inhibitor; BCL2/BCL2L1 Inhibitor; Bcl-2 Family Protein Inhibitor; Research Compound 2180923-05-9; BH3 Mimetic (potential class)
EINECS	Contact for details

Quality Control

Our research-grade biochemicals are produced and handled under strict quality management protocols. Each batch of Bcl-2/Bcl-Xl Inhibitor 1 undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.