Description

7-Despropyl 7-Methyl Vardenafil is a key pharmaceutical intermediate and reference standard used in the research and development of active pharmaceutical ingredients (APIs). This compound is of significant value for its role in the synthesis and analytical characterization of PDE5 inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, quality control departments, and manufacturers specializing in cardiovascular and urological therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Vardenafil and related PDE5 inhibitor APIs.
• Reference Standard: Used for analytical method development, validation, and quality control testing in pharmaceutical manufacturing.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for drug development programs.
• Impurity Profiling: Serves as a known impurity or degradation product standard to ensure API purity and compliance with ICH guidelines.
• Research Chemical: Used in biochemical and pharmacological research to study PDE5 enzyme inhibition and structure-activity relationships (SAR).

Basic Information

Product Name	7-Despropyl 7-Methyl Vardenafil
CAS No.	2169247-39-4
Molecular Formula	C21H29N5O4
Molecular Weight	415.49 g/mol
Synonyms	7-Despropyl-7-methylvardenafil; 2-[2-Ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one derivative; Despropyl Methyl Vardenafil; Vardenafil Impurity; Vardenafil Related Compound; PDE5 Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our 7-Despropyl 7-Methyl Vardenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the stringent requirements for pharmaceutical intermediates and reference standards. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific pharmacopeial or client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.