Description

3-Fluoro-4-Methyl-5-(Trifluoromethyl)Benzenesulfonamide is a high-value, multi-fluorinated benzenesulfonamide derivative, a key structural motif in modern chemical synthesis. This compound matters for its role as a sophisticated building block in the development of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine substitution pattern can dramatically alter molecular properties. Industrial researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical sectors need this material for lead optimization and the creation of novel compounds with enhanced metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in areas targeting kinases, GPCRs, and other enzymes where the sulfonamide and fluorine groups are pharmacologically advantageous.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and fluorine groups contribute to lipophilicity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of activity-based probes and molecular tags for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3-Fluoro-4-Methyl-5-(Trifluoromethyl)Benzenesulfonamide
CAS No.	2149597-25-9
Molecular Formula	C8H7F4NO2S
Molecular Weight	257.21 g/mol
Synonyms	3-Fluoro-4-methyl-5-(trifluoromethyl)benzenesulfonamide; 5-(Trifluoromethyl)-3-fluoro-4-methylbenzenesulfonamide; 4-Methyl-3-fluoro-5-(trifluoromethyl)benzenesulfonamide; Benzenesulfonamide, 3-fluoro-4-methyl-5-(trifluoromethyl)-; CAS 2149597-25-9
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-4-Methyl-5-(Trifluoromethyl)Benzenesulfonamide is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR and/or NMR), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.