Description

4-Chloro-n-Tosylbenzenesulfonimidoyl Fluoride is a specialized organosulfur and organofluorine compound that serves as a high-value synthetic intermediate. Its unique sulfonimidoyl fluoride functional group makes it a critical reagent for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the creation of new pesticides and herbicides, leveraging its sulfonimidoyl group for bioactivity.
• Chemical Biology Probes: Acts as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent inhibitors.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers with unique properties.
• Sulfonimidoyl Chemistry: A versatile precursor for further functionalization to create a library of sulfoximines and related derivatives.
• Catalyst & Ligand Development: Serves as a precursor for chiral auxiliaries or ligands in asymmetric synthesis.

Basic Information

Product Name	4-Chloro-n-Tosylbenzenesulfonimidoyl Fluoride
CAS No.	2143892-50-4
Molecular Formula	C13H11ClFNO2S2
Molecular Weight	339.81 g/mol
Synonyms	4-Chloro-N-(4-methylphenyl)sulfonylbenzenesulfonimidoyl fluoride; 4-Chloro-N-tosylbenzenesulfonimidoyl fluoride; Benzenesulfonimidoyl fluoride, 4-chloro-N-[(4-methylphenyl)sulfonyl]-; p-Chloro-N-(p-tolylsulfonyl)benzenesulfonimidoyl fluoride; 4-Chloro-N-(p-toluenesulfonyl)benzenesulfonimidoyl fluoride; 4-Chloro-N-tosylbenzenesulfonimidoyl fluoride; Sulfonimidoyl Fluoride Intermediate
EINECS	Contact for details

Quality Control

Our 4-Chloro-n-Tosylbenzenesulfonimidoyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.