Description

Pf-06700841-Tsoh is a high-purity, small molecule active pharmaceutical ingredient (API) and research chemical, supplied under the CAS registry number 2140301-96-6. This compound is a critical intermediate and reference standard for pharmaceutical research and development, particularly in the field of kinase inhibition. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality materials for drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical R&D: Primary use as a reference standard and key intermediate in the synthesis and development of novel therapeutic agents.
• Kinase Inhibitor Studies: Serves as a crucial tool compound for investigating specific kinase pathways in biochemical and cellular assays.
• Process Chemistry: Used as a starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Analytical Method Development: Employed as a certified reference material for establishing and validating HPLC, LC-MS, and other analytical techniques.
• Preclinical Research: Utilized in in vitro and in vivo studies to evaluate pharmacokinetics, pharmacodynamics, and efficacy.
• Quality Control Laboratories: Acts as a system suitability standard and for impurity identification in batch release testing.

Basic Information

Product Name	Pf-06700841-Tsoh
CAS No.	2140301-96-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF-06700841 tosylate; PF 06700841 TSO; PF06700841-Tsoh; 2140301-96-6; BMS-986165 related compound; Tyk2/Jak1 Inhibitor PF-06700841 tosylate salt; (3S,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Pf-06700841-Tsoh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS), purity assessment by HPLC, and control of residual solvents and impurities to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.