Description

Ampd2 Inhibitor 1 is a potent and selective small molecule inhibitor of adenosine monophosphate deaminase 2 (AMPD2), a key enzyme in the purine metabolism pathway. This compound is a critical research tool for investigating the role of AMPD2 in cellular energy regulation, nucleotide metabolism, and related disease pathologies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic disorders, cardiovascular research, and ischemia-reperfusion injury studies.

Application

• Biochemical Research: Used as a selective pharmacological tool to study AMPD2 enzyme kinetics and inhibition mechanisms in vitro.
• Cell-Based Assays: Employed to investigate the effects of AMPD2 inhibition on cellular energy metabolism, nucleotide pools, and viability in various cell lines.
• Preclinical Disease Modeling: Applied in animal models to explore the therapeutic potential of AMPD2 inhibition for conditions like heart failure, metabolic syndrome, and muscle disorders.
• Target Validation: Serves as a key compound for validating AMPD2 as a drug target in early-stage discovery programs.
• High-Throughput Screening (HTS): Can be used as a reference standard or positive control in HTS campaigns to identify novel AMPD2 modulators.

Basic Information

Product Name	Ampd2 Inhibitor 1
CAS No.	2139356-35-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AMPD2 Inhibitor 1; AMPD2 Inhibitor; Adenosine Monophosphate Deaminase 2 Inhibitor 1; (S)-2-(4-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)butyl)isoindoline-1,3-dione (common structural analog class); Purine Metabolism Inhibitor; Research Compound 2139356-35-5.
EINECS	Contact for details

Quality Control

Our Ampd2 Inhibitor 1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, MS) and purity assessment by HPLC to ensure high chemical and isomeric purity suitable for research applications. A detailed Certificate of Analysis (COA) containing batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.