Description

Cd73-In-1 is a potent and selective small molecule inhibitor of the ecto-5'-nucleotidase (CD73) enzyme. This compound is crucial for researchers investigating the adenosine signaling pathway, which plays a significant role in immune regulation and tumor microenvironment modulation. It is primarily utilized by pharmaceutical R&D teams and academic laboratories focused on oncology, immunology, and inflammatory disease research. The high-purity material ensures reliable and reproducible results in biochemical and cellular assays.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying CD73 enzyme kinetics and inhibition mechanisms.
• Oncology Research: Investigated for its potential to modulate the tumor microenvironment by blocking adenosine production, which may enhance anti-tumor immune responses.
• Immunology Studies: Applied in vitro and in vivo to understand the role of CD73 in immune cell function, T-cell activation, and immunosuppression.
• Drug Discovery & Development: Serves as a key pharmacophore or lead compound for the design and synthesis of novel CD73-targeting therapeutics.
• Inflammatory Disease Models: Used to probe the adenosine pathway's involvement in conditions like rheumatoid arthritis, colitis, and other autoimmune disorders.
• Cell-Based Assays: Employed to validate CD73 activity and screen for synergistic effects with other immunomodulatory agents.

Basic Information

Product Name	Cd73-In-1
CAS No.	2132396-40-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CD73 inhibitor 1; 5'-Nucleotidase Inhibitor; Ecto-5'-nucleotidase Inhibitor; Adenosine Signaling Inhibitor; Research Compound 2132396-40-6; CD73-IN-1; Small Molecule CD73 Antagonist
EINECS	Contact for details

Quality Control

Our Cd73-In-1 is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We adhere to relevant industry standards to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.