Description

Atropine-D5 is a deuterium-labeled analog of the naturally occurring tropane alkaloid atropine, specifically designed for use as an internal standard in analytical chemistry. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and precision of quantitative analyses, particularly in mass spectrometry-based methods. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics industries who require reliable quantification of atropine and related substances.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of atropine in biological matrices (e.g., plasma, urine, tissue).
• Metabolic and pharmacokinetic studies to track the absorption, distribution, metabolism, and excretion (ADME) of atropine.
• Pharmaceutical quality control and impurity profiling of atropine-containing drug formulations.
• Forensic and toxicological analysis for the accurate determination of atropine in casework samples.
• Method development and validation in analytical laboratories to meet regulatory compliance (e.g., FDA, EMA).
• Isotope dilution mass spectrometry (IDMS) for achieving the highest level of measurement certainty.

Basic Information

Product Name	Atropine-D5
CAS No.	2124269-77-6
Molecular Formula	C17H18D5NO3
Molecular Weight	294.40 g/mol (approx.)
Synonyms	(±)-Hyoscyamine-D5; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate-D5; Tropine tropate-D5; DL-Hyoscyamine-D5; Atropine-d5; Deuterated Atropine; [2H5]-Atropine
EINECS	Contact for details

Quality Control

Every batch of Atropine-D5 is manufactured and analyzed under strict quality management systems to ensure the highest isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity, ensuring compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.