Description

1-Benzyloxy-2-Bromo-6-Chloro-4-Fluorobenzene is a high-purity, multi-substituted aromatic building block of significant value in advanced organic synthesis. Its unique halogen and benzyloxy substitution pattern makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the halogen atoms are crucial for biological activity and environmental stability.
• Material Science Research: Acts as a monomer or building block for creating specialty polymers, liquid crystals, or organic electronic materials with tailored properties.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions due to its reactive bromo and chloro substituents.
• Academic & Contract Research: Essential for methodological studies and library synthesis in university and CRO (Contract Research Organization) laboratories exploring new chemical spaces.

Basic Information

Product Name	1-Benzyloxy-2-Bromo-6-Chloro-4-Fluorobenzene
CAS No.	2121512-74-9
Molecular Formula	C₁₃H₉BrClFO
Molecular Weight	315.56 g/mol
Synonyms	2-Bromo-6-chloro-4-fluoro-1-(phenylmethoxy)benzene; 1-(Benzyloxy)-2-bromo-6-chloro-4-fluorobenzene; Benzene, 1-(benzyloxy)-2-bromo-6-chloro-4-fluoro-; 4-Fluoro-2-bromo-6-chloro-1-benzyloxybenzene; 2-Bromo-6-chloro-4-fluorophenyl benzyl ether
EINECS	Contact for details

Quality Control

Our 1-Benzyloxy-2-Bromo-6-Chloro-4-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee reliable performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.