Description

[2-Fluoro-5-(Methylsulfanyl)Pyridin-3-Yl]Boronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block essential for modern cross-coupling chemistry. Its core value lies in enabling the efficient, selective construction of complex heterocyclic scaffolds, which are pivotal in advanced material and pharmaceutical research. This compound is critically needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for constructing complex, fluorinated pyridine derivatives used in drug discovery and development.
• Agrochemical Synthesis: Employed in the research and production of advanced crop protection agents, leveraging the unique properties of the fluorine and methylthio substituents.
• Material Science Research: Used to synthesize novel organic electronic materials, ligands for catalysis, and other functional molecules where precise molecular architecture is required.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or probes used to study biological pathways and target engagement.
• Process Chemistry & Scale-up: Provides a stable, handleable boronic ester derivative for optimizing and scaling synthetic routes in pilot plants and manufacturing.

Basic Information

Product Name	[2-Fluoro-5-(Methylsulfanyl)Pyridin-3-Yl]Boronic Acid Pinacol Ester
CAS No.	2121512-24-9
Molecular Formula	C₁₃H₁₇BFNO₂S
Molecular Weight	281.15 g/mol
Synonyms	2-Fluoro-5-(methylthio)pyridine-3-boronic acid pinacol ester; (2-Fluoro-5-(methylsulfanyl)-3-pyridinyl)boronic acid pinacol ester; 5-(Methylthio)-2-fluoropyridine-3-boronic acid pinacol ester; [2-Fluoro-5-(methylthio)-3-pyridyl]boronic acid pinacol ester; Boronic acid, B-[2-fluoro-5-(methylthio)-3-pyridinyl]-, 1,1-dimethylethyl ester; 3-Pyridineboronic acid, 2-fluoro-5-(methylthio)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of [2-Fluoro-5-(Methylsulfanyl)Pyridin-3-Yl]Boronic Acid Pinacol Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.