Description

Methyl 1-[6-(Trifluoromethyl)-3-Pyridyl]Cyclopropanecarboxylate is a high-value trifluoromethylpyridine derivative, a key structural motif prized for its ability to modulate the physicochemical properties of advanced molecules. This compound is specifically engineered to serve as a critical synthetic intermediate in the development of novel active ingredients. It is primarily targeted at research and development teams within the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with enhanced metabolic stability, bioavailability, and target binding affinity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Intermediate: Used in the research and production of next-generation herbicides, insecticides, and fungicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biochemical research.
• Material Science Research: Investigated as a precursor for specialty polymers and advanced organic electronic materials due to its unique electronic properties imparted by the fluorine atoms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 1-[6-(Trifluoromethyl)-3-Pyridyl]Cyclopropanecarboxylate
CAS No.	2119721-57-0
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	Methyl 1-(6-(trifluoromethyl)pyridin-3-yl)cyclopropanecarboxylate; 1-[6-(Trifluoromethyl)-3-pyridinyl]cyclopropanecarboxylic Acid Methyl Ester; Cyclopropanecarboxylic acid, 1-[6-(trifluoromethyl)-3-pyridinyl]-, methyl ester; 3-Pyridinecyclopropanecarboxylic acid, 6-(trifluoromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 1-[6-(Trifluoromethyl)-3-Pyridyl]Cyclopropanecarboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.