Description

(3R)-7-Fluoro-2,3-Dihydro-1-Benzofuran-3-Amine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its defined stereochemistry and functional group, which are critical for the synthesis of active pharmaceutical ingredients (APIs) and advanced organic molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of central nervous system (CNS) active drugs and other therapeutic candidates.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral scaffold in the development of new catalytic systems.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & R&D: Utilized in university and corporate laboratories for medicinal chemistry programs and methodological studies.
• Process Chemistry Development: Acts as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(3R)-7-Fluoro-2,3-Dihydro-1-Benzofuran-3-Amine Hydrochloride
CAS No.	2102410-16-0
Molecular Formula	C8H9ClFNO
Molecular Weight	189.61 g/mol
Synonyms	(3R)-7-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride; (R)-7-Fluoro-2,3-dihydro-1-benzofuran-3-amine HCl; 7-Fluoro-2,3-dihydro-(3R)-benzofuran-3-amine hydrochloride; (3R)-7-Fluoro-2,3-dihydrobenzo[b]furan-3-amine hydrochloride; (R)-7-Fluoro-2,3-dihydrobenzofuran-3-amine hydrochloride; (3R)-7-Fluoro-2,3-dihydro-1-benzofuran-3-amine HCl salt; 2102410-16-0; Amine, (3R)-7-fluoro-2,3-dihydro-1-benzofuran-3-, hydrochloride
EINECS	Contact for details

Quality Control

Our (3R)-7-Fluoro-2,3-Dihydro-1-Benzofuran-3-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC/Chiral HPLC purity, optical rotation, and identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with customer specifications. Our quality system supports development under ISO and cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.