Description

Gboxin CAS NO 2101315-36-8 is a high-purity, small-molecule compound of significant interest in pharmaceutical and biochemical research. Its primary value lies in its role as a potent and selective inhibitor of mitochondrial oxidative phosphorylation, specifically targeting the F0F1-ATP synthase complex. This makes it a critical research tool for studying cellular metabolism, cancer biology, and neurodegenerative diseases. It is essential for researchers and developers in the fields of oncology, neuropharmacology, and metabolic disorder therapeutics.

Application

• Oncology Research: Used to investigate the Warburg effect and target cancer cell metabolism, particularly in glioblastoma and other solid tumor models.
• Neurodegenerative Disease Studies: Applied in research on Alzheimer's, Parkinson's, and other disorders linked to mitochondrial dysfunction.
• Biochemical Mechanism Studies: Serves as a specific tool compound to study the function and inhibition of mitochondrial ATP synthase.
• Drug Discovery & Development: Employed as a reference standard or lead compound in high-throughput screening and preclinical development of novel anti-cancer agents.
• Cell Biology & Metabolism: Utilized to induce metabolic stress and study cellular bioenergetics, apoptosis, and autophagy pathways.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in biochemistry and molecular biology.

Basic Information

Product Name	Gboxin
CAS No.	2101315-36-8
Molecular Formula	C23H21N3O4S
Molecular Weight	435.50 g/mol
Synonyms	Gboxin; 4-[[4-[(4-Methoxyphenyl)sulfonyl]-1-piperazinyl]sulfonyl]-N-(2-phenylethyl)benzamide; ATP Synthase Inhibitor, Gboxin; Mitochondrial OxPhos Inhibitor Gboxin; Glioblastoma Inhibitor Gboxin
EINECS	Contact for details

Quality Control

Our Gboxin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your research integrity and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.