Description

Cdk4/6/1 Inhibitor CAS NO 2099128-41-1 is a potent and selective small molecule inhibitor targeting the cyclin-dependent kinases 4, 6, and 1, which are critical regulators of the cell cycle. This compound is a vital research tool for investigating cell cycle progression, proliferation mechanisms, and the development of novel oncology therapeutics. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on cancer biology and drug discovery.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic assays to study the specific roles and inhibition profiles of CDK4, CDK6, and CDK1.
• Cell Biology Studies: Applied in cell-based assays to investigate cell cycle arrest, proliferation pathways, and the effects of CDK inhibition on various cancer cell lines.
• Drug Discovery & Development: Serves as a key reference compound or lead molecule in the screening and optimization of novel anti-cancer agents targeting the cell cycle.
• Mechanism of Action (MoA) Studies: Utilized to elucidate the downstream signaling pathways and therapeutic potential of CDK4/6/1 inhibition in preclinical models.
• Academic Research: A critical reagent for fundamental research in oncology, molecular biology, and genetics related to cell cycle dysregulation.

Basic Information

Product Name	Cdk4/6/1 Inhibitor
CAS No.	2099128-41-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CDK4/6/1 Inhibitor; CDK4/6/1i; CAS 2099128-41-1; Cyclin-dependent kinase 4/6/1 inhibitor; CDK4/6/1 inhibitor compound; Cell cycle kinase inhibitor 2099128-41-1; Research compound 2099128-41-1
EINECS	Contact for details

Quality Control

Our Cdk4/6/1 Inhibitor is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation and purity assessment via advanced chromatographic methods. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.