Description

2-Chloro-4-Fluoropyridine-5-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the development of organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Diagnostics: Utilized in the creation of molecular probes and sensor materials for biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Chloro-4-Fluoropyridine-5-Boronic Acid
CAS No.	2096341-49-8
Molecular Formula	C5H4BClFNO2
Molecular Weight	174.36 g/mol
Synonyms	(2-Chloro-4-fluoropyridin-5-yl)boronic acid; 5-Borono-2-chloro-4-fluoropyridine; 2-Chloro-4-fluoro-5-pyridineboronic acid; 2-Chloro-4-fluoropyridine-5-boronic acid pinacol ester (common derivative); 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-chloro-4-fluoropyridine; 2-Chloro-4-fluoro-5-pyridinylboronic acid; 2096341-49-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoropyridine-5-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards expected for pharmaceutical development and other high-precision applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.