Description

6-(Cyclopentyloxy)-2-Fluoropyridine-3-Boronic Acid is a high-value, multi-functional boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used to construct heterocyclic cores found in modern herbicides, fungicides, and insecticides, contributing to improved efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and charge-transport molecules, due to its functionalized pyridine-boronic acid structure.
• Chemical Biology Probes: Serves as a versatile handle for bioconjugation and the development of activity-based probes and diagnostic agents.
• Catalyst Ligand Development: The cyclopentyloxy and fluoropyridine motifs can be utilized to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential raw material for CDMOs (Contract Development and Manufacturing Organizations) specializing in custom, small-scale API synthesis for clinical trials.

Basic Information

Item	Details
Product Name	6-(Cyclopentyloxy)-2-Fluoropyridine-3-Boronic Acid
CAS No.	2096339-69-2
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	2-Fluoro-6-(cyclopentyloxy)pyridine-3-boronic acid; (2-Fluoro-6-cyclopentyloxypyridin-3-yl)boronic acid; 3-Borono-2-fluoro-6-(cyclopentyloxy)pyridine; 6-Cyclopentyloxy-2-fluoropyridine-3-boronic Acid; 2096339-69-2; 2-Fluoro-6-cyclopentyloxy-3-pyridineboronic acid
EINECS	Contact for details

Quality Control

Every batch of 6-(Cyclopentyloxy)-2-Fluoropyridine-3-Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its boronic acid nature, the material is moisture-sensitive; containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.