Description

Erk1/2 Inhibitor 1 CAS NO 2095719-90-5 is a potent and selective small molecule inhibitor of the extracellular signal-regulated kinases 1 and 2 (ERK1/2), key components of the MAPK/ERK signaling pathway. This compound is a critical research tool for investigating cellular proliferation, differentiation, and survival mechanisms, with significant implications for oncology and disease modeling. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in signal transduction studies and preclinical drug discovery.

Application

• Biomedical Research: A fundamental tool for studying the role of the MAPK/ERK pathway in various cellular processes and disease states.
• Oncology Research: Used to investigate tumor cell proliferation, survival, and resistance mechanisms in cancer cell lines and animal models.
• Drug Discovery & Development: Serves as a reference compound and pharmacological probe for screening and validating novel ERK-targeted therapeutics.
• Signal Transduction Studies: Enables precise dissection of upstream and downstream effects of ERK1/2 activation in specific biological contexts.
• Academic & Institutional Research: Supports basic science investigations in molecular biology, biochemistry, and pharmacology.
• Biomarker Development: Aids in correlating pathway inhibition with phenotypic responses for companion diagnostic research.

Basic Information

Product Name	Erk1/2 Inhibitor 1
CAS No.	2095719-90-5
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.42 g/mol
Synonyms	ERK1/2 Inhibitor I; ERK Inhibitor I; BVD-523 (Analog/Related); Ulixertinib (Analog/Related); (S)-1-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-3-(4-(6-oxo-1,6-dihydropyridazin-3-yl)phenyl)urea; GDC-0994 (Analog/Related); Ravoxertinib (Analog/Related); MAPK Inhibitor
EINECS	Contact for details

Quality Control

Our Erk1/2 Inhibitor 1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and potency are provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake. Store away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity (IC50)	Reported with COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.