Description

Bml-284 Hcl is a potent and selective small molecule inhibitor of the Wnt/β-catenin signaling pathway, a critical target in biomedical research and therapeutic development. This compound is essential for researchers investigating cell fate determination, tissue regeneration, and oncogenesis, where dysregulated Wnt signaling is a key driver. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, stem cell biology, and regenerative medicine.

Application

• Biomedical Research: A key tool for studying the molecular mechanisms of the Wnt/β-catenin signaling pathway in vitro and in vivo.
• Oncology Research: Used to investigate and validate the Wnt pathway as a therapeutic target in various cancers, including colorectal, breast, and liver cancer.
• Stem Cell Studies: Applied to modulate Wnt signaling to control stem cell self-renewal, differentiation, and pluripotency.
• Drug Discovery & Development: Serves as a reference compound or pharmacologic probe in high-throughput screening and lead optimization campaigns.
• Regenerative Medicine: Explored for its potential to influence tissue repair and regeneration processes by targeting specific signaling cascades.
• Academic & Institutional Research: A standard reagent for molecular biology and biochemistry laboratories worldwide.

Basic Information

Product Name	Bml-284 Hcl
CAS No.	2095432-75-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BML-284 hydrochloride; BML 284 HCl; Wnt/β-catenin pathway inhibitor BML-284; 2-(4-(2-Methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide hydrochloride
EINECS	Contact for details

Quality Control

Our Bml-284 Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, potency, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.