Description

3-Bromo-2-Chloro-6-Fluorobenzotrifluoride is a high-value, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine, chlorine, fluorine, and a trifluoromethyl group, makes it a versatile precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Active Ingredient Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen pattern influences bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine and chlorine substituents offer orthogonal reactivity for sequential Suzuki, Stille, or Buchwald-Hartwig amination reactions to build complex architectures.
• Fluorine Chemistry Research: An important substrate for studying the effects of multiple halogen substitutions, including fluorine, on molecular properties and reactivity.
• Chemical Intermediate for Dyes and Pigments: Used in the synthesis of specialized halogenated dyes and pigments with enhanced lightfastness and chemical resistance.

Basic Information

Product Name	3-Bromo-2-Chloro-6-Fluorobenzotrifluoride
CAS No.	2091146-38-0
Molecular Formula	C7H2BrClF4
Molecular Weight	277.44 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-5-(trifluoromethyl)benzene; 2-Chloro-3-fluoro-5-(trifluoromethyl)bromobenzene; 3-Bromo-2-chloro-6-fluoro-α,α,α-trifluorotoluene; 3-Bromo-2-chloro-6-fluoro(trifluoromethyl)benzene; Benzene, 1-bromo-2-chloro-3-fluoro-5-(trifluoromethyl)-; 2-Chloro-3-fluoro-5-(trifluoromethyl)-1-bromobenzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-6-Fluorobenzotrifluoride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications. Our quality systems are designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.