Description

Benzene, 1-Bromo-5-(Bromomethyl)-2-Fluoro-4-Methyl- is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of specialty monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituents make it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl and conjugated systems.
• Fluorine Chemistry Studies: Acts as a model compound in methodological development for introducing and manipulating fluorine-containing aromatic groups.

Basic Information

Product Name	Benzene, 1-Bromo-5-(Bromomethyl)-2-Fluoro-4-Methyl-
CAS No.	2090556-05-9
Molecular Formula	C8H7Br2F
Molecular Weight	281.95 g/mol
Synonyms	1-Bromo-5-(bromomethyl)-2-fluoro-4-methylbenzene; 2-Fluoro-4-methyl-1,5-bis(bromomethyl)benzene; 2-Fluoro-α,α'-dibromo-p-xylene; 4-Methyl-2-fluoro-1,5-bis(bromomethyl)benzene; 1,5-Bis(bromomethyl)-2-fluoro-4-methylbenzene; 2-Fluoro-4-methyl-1,5-dibromomethylbenzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-5-(Bromomethyl)-2-Fluoro-4-Methyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.