Description

Selective Pi3Kδ Inhibitor 1 CAS NO 2088525-31-7 is a potent and selective small molecule inhibitor targeting the delta isoform of phosphoinositide 3-kinase (PI3Kδ). This compound is of significant value for research and development in immunology and oncology, as selective inhibition of PI3Kδ offers a targeted approach to modulate immune cell function and signaling pathways. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in developing novel therapeutics for autoimmune diseases, inflammatory conditions, and hematological cancers.

Application

• Biochemical Research: Used as a critical tool compound for studying the role of PI3Kδ signaling in B-cell activation, proliferation, and survival.
• Drug Discovery & Development: Serves as a reference standard or lead compound in the development of novel immunomodulatory and anti-cancer agents.
• Target Validation: Employed in cellular and in vivo models to validate PI3Kδ as a therapeutic target for conditions like rheumatoid arthritis, asthma, and chronic lymphocytic leukemia (CLL).
• Mechanistic Studies: Facilitates the investigation of downstream effectors and cross-talk within the PI3K/AKT/mTOR and related signaling networks.
• High-Throughput Screening (HTS): Acts as a control or benchmark in screening assays designed to identify new PI3Kδ inhibitors or assess compound selectivity.
• Preclinical Pharmacology: Utilized in pharmacokinetic (PK), pharmacodynamic (PD), and efficacy studies in relevant disease models.

Basic Information

Product Name	Selective Pi3Kδ Inhibitor 1
CAS No.	2088525-31-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PI3Kδ Inhibitor 1; Selective PI3K Delta Inhibitor 1; PI3K-delta Inhibitor 1; (S)-2-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)amino)-N-(5-(4-methylpiperazin-1-yl)pentyl)benzamide; 2088525-31-7; PI3Kδi 1
EINECS	Contact for details

Quality Control

Our Selective Pi3Kδ Inhibitor 1 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.