Description

Cdk2 Inhibitor 73 is a potent and selective small molecule inhibitor of cyclin-dependent kinase 2 (Cdk2), a key regulator of the cell cycle. This compound is a critical research tool for investigating cell cycle progression, DNA replication, and the mechanisms of oncogenesis in various cancer models. It is essential for pharmaceutical R&D, academic research, and biotechnology companies focused on developing novel cancer therapeutics and understanding cellular proliferation pathways.

Application

• Biochemical Research: Used as a selective inhibitor to study the specific role of Cdk2 in cell cycle regulation and signal transduction pathways in vitro.
• Oncology Drug Discovery: Serves as a lead compound or reference standard in high-throughput screening and structure-activity relationship (SAR) studies for developing novel anti-cancer agents.
• Cellular Mechanism Studies: Applied in cell-based assays to investigate the effects of Cdk2 inhibition on apoptosis, senescence, and proliferation in various cancer cell lines.
• Academic Research: A vital reagent for universities and research institutes exploring fundamental biology related to cell division, checkpoint control, and tumorigenesis.
• Preclinical Development: Utilized in animal models to evaluate the pharmacokinetics, efficacy, and safety profiles of Cdk2-targeting therapeutic candidates.

Basic Information

Product Name	Cdk2 Inhibitor 73
CAS No.	2079895-42-2
Molecular Formula	C₂₀H₂₀N₈O₂
Molecular Weight	404.43 g/mol
Synonyms	CDK2 Inhibitor 73; Cdk2 Inhibitor III; 2-((5-((4-Ethylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide; 2-({5-[(4-Ethyl-1-piperazinyl)methyl]-1H-benzimidazol-2-yl}thio)-N-2-thiazolylacetamide; BDBM50180973; HY-101872; SML1843; CHEMBL3186392
EINECS	Contact for details

Quality Control

Our Cdk2 Inhibitor 73 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.