Description

Casein Kinase Inhibitor A51 is a potent and selective small molecule inhibitor targeting specific casein kinase isoforms, crucial for modulating key cellular signaling pathways. This high-purity biochemical tool is essential for researchers investigating protein phosphorylation, cell cycle regulation, and disease mechanisms in oncology and neurology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies for target validation, lead optimization, and mechanistic studies.

Application

• Biochemical Research: Used as a selective tool compound to study casein kinase-mediated phosphorylation events and signal transduction pathways in vitro.
• Oncology Research: Investigated for its potential to inhibit cancer cell proliferation and induce apoptosis in various preclinical models.
• Neuroscience Studies: Applied in research exploring the role of casein kinases in neurodegenerative diseases and neuronal development.
• Cell Biology: Employed to dissect the function of casein kinases in cell cycle control, DNA damage response, and circadian rhythms.
• Drug Discovery: Serves as a reference standard and a starting point for the development of novel therapeutic agents targeting kinase activity.
• High-Throughput Screening (HTS): Utilized in assay development and validation for screening compound libraries against casein kinase targets.

Basic Information

Product Name	Casein Kinase Inhibitor A51
CAS No.	2079068-74-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	A51; CK1 Inhibitor A51; Casein Kinase 1 Inhibitor A51; Casein Kinase Inhibitor A-51; 2079068-74-7; (Chemical name to be confirmed)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade biochemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (e.g., by NMR/MS), and other relevant parameters are available upon request to support your research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.