Description

5-Bromo-2-(2-Fluoro-2-Propyl)Pyridine is a high-purity halogenated pyridine derivative, a crucial building block in modern organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a precursor for creating advanced herbicides, fungicides, and insecticides, leveraging the bioactivity imparted by the halogenated pyridine core.
• Material Science Research: Used in the development of specialty chemicals, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form biaryl structures.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for biological screening.

Basic Information

Product Name	5-Bromo-2-(2-Fluoro-2-Propyl)Pyridine
CAS No.	2070867-74-0
Molecular Formula	C8H9BrFN
Molecular Weight	218.07 g/mol
Synonyms	2-(2-Fluoro-2-propyl)-5-bromopyridine; 5-Bromo-2-(2-fluoropropan-2-yl)pyridine; 5-Bromo-2-(1-fluoro-1-methylethyl)pyridine; 2-(1-Fluoro-1-methylethyl)-5-bromopyridine; 5-Bromo-2-(α-fluoroisopropyl)pyridine; 5-Bromo-2-(2-fluoroisopropyl)pyridine; 2070867-74-0
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(2-Fluoro-2-Propyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.