Description

(S)-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine Dihydrochloride is a high-purity chiral amine building block, specifically the (S)-enantiomer, with a trifluoromethylpyridine core. This compound is critical for pharmaceutical research and development, offering a valuable scaffold for creating novel active ingredients with enhanced metabolic stability and bioavailability. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of targeted small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the chiral center and fluorine atoms contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Item	Detail
Product Name	(S)-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine Dihydrochloride
CAS No.	2061996-71-0
Molecular Formula	C8H10Cl2F3N2
Molecular Weight	263.08 g/mol
Synonyms	(S)-1-[5-(Trifluoromethyl)-2-pyridinyl]ethanamine dihydrochloride; (S)-1-(5-(Trifluoromethyl)pyridin-2-yl)ethan-1-amine dihydrochloride; (S)-α-Methyl-5-(trifluoromethyl)-2-pyridineethanamine dihydrochloride; (S)-1-(5-Trifluoromethyl-2-pyridyl)ethylamine dihydrochloride; (S)-2-(1-Aminoethyl)-5-(trifluoromethyl)pyridine dihydrochloride; (S)-1-(5-CF3-Pyridin-2-yl)-ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine Dihydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.