Description

(1R)-1-(6-Fluoro(2-Pyridyl))Ethylamine Dihydrochloride is a high-purity chiral amine building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a key intermediate for synthesizing novel, biologically active molecules, particularly in the creation of targeted therapeutics. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and fine chemical synthesis who require reliable access to enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical entities with potential therapeutic effects.
• Agrochemical Synthesis: Serves as a building block for developing advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(1R)-1-(6-Fluoro(2-Pyridyl))Ethylamine Dihydrochloride
CAS No.	2061996-65-2
Molecular Formula	C7H10Cl2FN2
Molecular Weight	209.07 g/mol
Synonyms	(1R)-1-(6-Fluoropyridin-2-yl)ethan-1-amine dihydrochloride; (R)-1-(6-Fluoropyridin-2-yl)ethanamine hydrochloride; (R)-1-(6-Fluoro-2-pyridinyl)ethylamine dihydrochloride; 2-Pyridineethanamine, 6-fluoro-α-methyl-, (αR)-, dihydrochloride; (R)-α-Methyl-6-fluoro-2-pyridineethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (1R)-1-(6-Fluoro(2-Pyridyl))Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (assay), chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.