Description

3-Fluoro-3-Phenylpiperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its unique structural features, which are critical for modulating biological activity and physicochemical properties in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly within the central nervous system (CNS) and metabolic disease research areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorination and piperidine substitution on potency and selectivity.
• CNS Drug Development: Serves as a precursor for potential candidates targeting neurological disorders, leveraging the piperidine scaffold common in many neuroactive compounds.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying enzyme function and receptor interactions.
• Process Chemistry & Scale-up: Supplied for route scouting, optimization, and pilot-scale synthesis during the development phase of new chemical entities.
• Academic Research: Used in university and institutional labs for synthetic methodology development and bioorganic chemistry studies.

Basic Information

Product Name	3-Fluoro-3-Phenylpiperidine Hydrochloride
CAS No.	2059970-47-5
Molecular Formula	C11H15ClFN
Molecular Weight	215.70 g/mol
Synonyms	3-Fluoro-3-phenylpiperidine HCl; 3-Fluoro-3-phenylpiperidine hydrochloride; 3-Phenyl-3-fluoropiperidine hydrochloride; Piperidine, 3-fluoro-3-phenyl-, hydrochloride (1:1); 3-Fluoro-3-phenylpiperidinium chloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-3-Phenylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.