Description

Stat3-In-1 CAS NO 2059952-75-7 is a potent and selective small molecule inhibitor designed to target the Signal Transducer and Activator of Transcription 3 (STAT3) signaling pathway. This compound is critical for researchers and developers in the life sciences sector, as it provides a powerful tool for studying oncogenesis, immune regulation, and inflammatory diseases. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel cancer therapeutics and targeted molecular therapies.

Application

• Oncology Research: Investigation of STAT3's role in tumor cell proliferation, survival, and metastasis across various cancer types.
• Drug Discovery & Development: Serving as a lead compound or reference standard in high-throughput screening and preclinical studies for novel anticancer agents.
• Immunology Studies: Exploring the modulation of immune responses and T-cell differentiation where STAT3 signaling is a key regulator.
• Inflammatory Disease Models: Research into conditions like rheumatoid arthritis and inflammatory bowel disease where STAT3 pathway dysregulation is implicated.
• Biochemical Assay Development: Use as a specific inhibitor in cell-based and biochemical assays to validate STAT3-dependent mechanisms.
• Academic & Contract Research: Fundamental research in molecular biology and signal transduction pathways within university and CRO laboratories.

Basic Information

Product Name	Stat3-In-1
CAS No.	2059952-75-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	STAT3-IN-1; STAT3 Inhibitor-1; STAT3 inhibitor Stat3-In-1; 2-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-6-hydroxy-4-methylquinoline; (E)-2-(3,4-Dimethoxystyryl)-6-hydroxy-4-methylquinoline; 2-[(E)-2-(3,4-Dimethoxyphenyl)vinyl]-6-hydroxy-4-methylquinoline
EINECS	Contact for details

Quality Control

Our Stat3-In-1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.