Description

Hdac3 Inhibitor CAS NO 2044701-99-5 is a potent and selective small molecule compound designed to specifically target and inhibit Histone Deacetylase 3 (HDAC3), a key enzyme involved in epigenetic regulation. This specificity makes it a critical research tool for investigating the role of HDAC3 in gene expression, cellular differentiation, and disease pathways. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on oncology, neurology, and metabolic disorders for target validation and preclinical drug discovery.

Application

• Biomedical Research: Used as a selective pharmacological probe to study the specific biological functions and signaling pathways of HDAC3 in cell culture and animal models.
• Drug Discovery & Target Validation: Serves as a lead compound or reference standard in high-throughput screening (HTS) campaigns and structure-activity relationship (SAR) studies for novel HDAC3-targeted therapeutics.
• Oncology Research: Investigated for its potential effects on cancer cell proliferation, apoptosis, and differentiation in various cancer types, including leukemia, lymphoma, and solid tumors.
• Neurological Disease Models: Applied in research models of neurodegenerative diseases (e.g., Alzheimer's, Huntington's) and neuropsychiatric disorders to explore HDAC3's role in neuronal function and survival.
• Metabolic Disorder Studies: Utilized in research on metabolic syndromes, diabetes, and non-alcoholic fatty liver disease (NAFLD) to understand epigenetic mechanisms in metabolism.
• Inflammation & Immunology: Employed to examine the modulation of immune cell function and inflammatory responses by HDAC3 inhibition.

Basic Information

Product Name	Hdac3 Inhibitor
CAS No.	2044701-99-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HDAC3 Inhibitor; Selective HDAC3 Inhibitor; HDAC3i; (S)-N-Hydroxy-4-(2-methyl-1,3-thiazol-4-yl)benzamide derivative; BRD3308; BRD-3308; HDAC III Inhibitor; Histone Deacetylase 3 Inhibitor
EINECS	Contact for details

Quality Control

Our Hdac3 Inhibitor is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure high batch-to-batch consistency and reliability for sensitive research applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.