Description

2-Methylbenzothiazole-6-Sulfonyl Chloride Hydrochloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, serving as a versatile electrophile for sulfonamide bond formation and a precursor for more complex heterocyclic systems. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key synthon for the development of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with sulfonyl moieties.
• Material Science Research: Used in the synthesis of functional polymers, dyes, and photoactive materials.
• Chemical Biology Probes: Employed in the design of activity-based probes (ABPs) and covalent inhibitors for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules and reference standards.

Basic Information

Product Name	2-Methylbenzothiazole-6-Sulfonyl Chloride Hydrochloride
CAS No.	2006277-66-1
Molecular Formula	C8H7Cl2NO2S2 • HCl
Molecular Weight	Contact for details
Synonyms	6-(Chlorosulfonyl)-2-methyl-1,3-benzothiazole Hydrochloride; 2-Methyl-6-sulfonylchloride benzothiazole HCl; 2-Methylbenzothiazole-6-sulfonylchloride hydrochloride salt; MBT-6-SC HCl; 2-Methylbenzo[d]thiazole-6-sulfonyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methylbenzothiazole-6-Sulfonyl Chloride Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.