Description

3,5-Difluoropicolinimidamide Hydrochloride is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibition. Pharmaceutical R&D teams and fine chemical manufacturers need this material for constructing complex molecular architectures where the difluoropyridine moiety is essential for modulating biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile scaffold for probe and tool compound discovery.
• Material Science: Potential building block for specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for novel heterocyclic chemistry studies.

Basic Information

Product Name	3,5-Difluoropicolinimidamide Hydrochloride
CAS No.	298709-32-7
Molecular Formula	C7H7ClF2N3
Molecular Weight	206.60 g/mol
Synonyms	3,5-Difluoropyridine-2-carboximidamide hydrochloride; 2-Pyridinecarboximidamide, 3,5-difluoro-, hydrochloride; 3,5-Difluoropicolinamidine hydrochloride; Picolinimidamide, 3,5-difluoro-, hydrochloride; 3,5-Difluoro-2-pyridinecarboximidamide monohydrochloride
EINECS	Contact for details

Quality Control

Our 3,5-Difluoropicolinimidamide Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.