Description

Bay 41-4109 is a potent and selective small molecule inhibitor of Hepatitis B virus (HBV) replication, targeting the viral core protein. This compound is of significant interest for antiviral research and the development of novel therapeutic agents against chronic HBV infection. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) engaged in virology and infectious disease studies.

Application

• Antiviral Research: A key reference standard and active pharmaceutical ingredient (API) in the investigation of Hepatitis B virus (HBV) lifecycle and inhibition mechanisms.
• Drug Discovery & Development: Serves as a crucial lead compound and pharmacological tool for developing new classes of anti-HBV therapeutics targeting the viral capsid assembly.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro assays to evaluate the efficacy of novel compounds against HBV core protein.
• Mechanistic Studies: Employed to study virus-host interactions, capsid disassembly, and the intracellular trafficking of viral components.
• Preclinical Evaluation: Utilized in animal models of HBV infection to assess pharmacokinetics, pharmacodynamics, and therapeutic potential.

Basic Information

Product Name	Bay 41-4109
CAS No.	298708-81-3
Molecular Formula	C₂₁H₁₉ClN₄O₃
Molecular Weight	410.85 g/mol
Synonyms	N-(4-Chlorophenyl)-2-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-3-oxo-5-isoquinolinecarboxamide; Bay-41-4109; BAY 41-4109; BAY41-4109; GLS4; HAP_R01; Hepatitis B Virus Core Protein Allosteric Modulator; HBV Capsid Assembly Modulator
EINECS	Contact for details

Quality Control

Our Bay 41-4109 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.