Description

2-(3-Fluorophenyl)-Pyrrolidine is a versatile fluorinated pyrrolidine derivative, a key structural motif in modern medicinal chemistry. This compound serves as a crucial chiral building block and intermediate for the synthesis of novel pharmaceutical candidates. It is primarily utilized by research and development organizations, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery programs targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS-targeting drugs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new pharmacophores.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric synthesis and catalysis.
• Agrochemical Synthesis: Potential intermediate in the research and development of advanced crop protection agents.
• Material Science Research: Investigated as a building block for specialty polymers and advanced organic materials.

Basic Information

Product Name	2-(3-Fluorophenyl)-Pyrrolidine
CAS No.	298690-72-9
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	2-(3-Fluorophenyl)pyrrolidine; 3-Fluoro-α-(2-pyrrolidinyl)benzene; 1-(3-Fluorophenyl)-2-pyrrolidine; Pyrrolidine, 2-(3-fluorophenyl)-; 2-(3-Fluorophenyl)-1-azacyclopentane; 3-Fluoro-2-pyrrolidinylbenzene; α-(3-Fluorophenyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 2-(3-Fluorophenyl)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.