Description

Fatostatin A is a potent and selective small-molecule inhibitor of sterol regulatory element-binding protein (SREBP) activation. This compound matters significantly for researchers as it provides a powerful tool to study lipid metabolism, cholesterol biosynthesis, and their roles in metabolic diseases and cancer. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic pathway analysis, oncology research, and drug discovery programs.

Application

• Biochemical Research: A key tool for investigating the SREBP pathway and its regulation of lipid and cholesterol homeostasis.
• Metabolic Disease Studies: Used in research models for obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD) to understand underlying mechanisms.
• Oncology Research: Employed to study the role of lipid metabolism and SREBP signaling in cancer cell proliferation and survival.
• Drug Discovery: Serves as a reference compound or lead molecule in screening and developing novel therapeutics targeting lipid synthesis pathways.
• Cell Biology: Utilized to dissect the cellular processes of lipogenesis and membrane biogenesis in various cell lines.

Basic Information

Product Name	Fatostatin A
CAS No.	298197-04-3
Molecular Formula	C29H44N2O3
Molecular Weight	468.68 g/mol
Synonyms	Fatostatin; Fatostatin A Hydrobromide (salt form); BZ-001; SREBP Inhibitor; 4-Methyl-2-(4-methylpiperazin-1-yl)-N-[4-(3-pyridinyl)phenyl]quinazolin-6-amine; SREBP pathway inhibitor; NSC 780937; Lipid synthesis inhibitor
EINECS	Contact for details

Quality Control

Our Fatostatin A is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals to guarantee reliable and reproducible results for your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.