Description

T0901317 is a potent and selective synthetic agonist for the liver X receptor (LXR), a nuclear receptor involved in cholesterol metabolism and inflammation. This high-purity compound is essential for pharmaceutical research and development, particularly in the study of metabolic and inflammatory pathways. It serves as a critical tool for researchers and developers in the pharmaceutical, biotechnology, and academic sectors, enabling the discovery of novel therapeutics for conditions like atherosclerosis and diabetes.

Application

• Pharmaceutical R&D: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of LXR-targeting therapies.
• Biochemical Research: Used as a molecular probe to study LXR signaling pathways, gene regulation, and cholesterol homeostasis in vitro and in vivo.
• Drug Discovery Screening: Employed in high-throughput screening assays to identify and validate new drug candidates that modulate LXR activity.
• Metabolic Disease Studies: Facilitates research into atherosclerosis, diabetes, and other lipid metabolism disorders by activating LXR.
• Inflammation and Immunology Research: Investigated for its role in modulating inflammatory responses linked to LXR activation.
• Academic & Institutional Research: Provides a reliable reagent for universities and research institutes conducting fundamental biological research.

Basic Information

Product Name	T0901317
CAS No.	293754-55-9
Molecular Formula	C24H22F3NO3S
Molecular Weight	461.50 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide; TO-901317; T0901317; GW3965 analog; LXR agonist T0901317; Liver X Receptor agonist
EINECS	Contact for details

Quality Control

Every batch of T0901317 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support regulatory submissions. A detailed Certificate of Analysis (COA) confirming specifications such as assay (by HPLC), related substances, and residual solvents is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.