Description

Mmp-2/Mmp-9 Inhibitor Iv is a potent, cell-permeable, and selective hydroxamate-based inhibitor of matrix metalloproteinases MMP-2 (Gelatinase A) and MMP-9 (Gelatinase B). This compound is a critical research tool for investigating the role of these enzymes in pathological processes such as tumor metastasis, angiogenesis, and inflammatory diseases. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurology, and cardiovascular disease research.

Application

• Biomedical Research: A key reagent for in vitro and in vivo studies on the mechanisms of cancer invasion, metastasis, and angiogenesis.
• Drug Discovery & Development: Used as a reference standard and pharmacological tool in high-throughput screening and lead optimization for novel MMP inhibitor therapeutics.
• Neurological Disease Models: Applied in research exploring the breakdown of the blood-brain barrier and neuroinflammation associated with conditions like stroke, Alzheimer's, and multiple sclerosis.
• Cardiovascular Research: Investigated in studies related to atherosclerotic plaque instability, aneurysm formation, and cardiac remodeling.
• Inflammatory Disease Studies: Used to elucidate the role of MMP-2/MMP-9 in rheumatoid arthritis, osteoarthritis, and chronic obstructive pulmonary disease (COPD).
• Biochemical Assay Development: Serves as a control compound for validating enzyme activity assays and testing assay kits targeting gelatinases.

Basic Information

Product Name	Mmp-2/Mmp-9 Inhibitor Iv
CAS No.	292605-14-2
Molecular Formula	C₂₀H₂₈N₄O₄
Molecular Weight	388.46 g/mol
Synonyms	MMP-2/MMP-9 Inhibitor IV; (2R)-2-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide; NSC 405020; SB-3CT analog; CAS 292605-14-2; Gelatinase Inhibitor IV; MMP Inhibitor IV
EINECS	Contact for details

Quality Control

Our Mmp-2/Mmp-9 Inhibitor Iv is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.