Description

Argadin CAS NO 289665-92-5 is a potent and selective inhibitor of the enzyme arginase, which plays a critical role in the urea cycle and nitric oxide metabolism. This compound is essential for researchers and developers in life sciences, providing a key tool for modulating L-arginine pathways. It is primarily utilized in biochemical research, pharmaceutical development, and as a reference standard in analytical laboratories.

Application

• Biochemical Research: Used as a selective arginase inhibitor to study the urea cycle, nitric oxide synthase (NOS) pathways, and polyamine metabolism in cellular and enzymatic assays.
• Pharmaceutical R&D: Serves as a lead compound or reference standard in the development of therapeutics targeting conditions like cardiovascular diseases, pulmonary hypertension, and certain cancers where arginase activity is implicated.
• Diagnostic Development: Employed in the formulation of diagnostic kits and assays for measuring arginase activity in biological samples.
• Academic Studies: A vital reagent for universities and research institutions investigating liver function, immunology, and metabolic disorders.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (HPLC, LC-MS) to ensure accuracy and compliance.

Basic Information

Product Name	Argadin
CAS No.	289665-92-5
Molecular Formula	C9H19N5O3
Molecular Weight	245.28 g/mol
Synonyms	Nω-Hydroxy-nor-L-arginine; Nor-NOHA; (2S)-2-Amino-6-[(E)-(hydroxyimino)methyl]amino]hexanoic acid; H-Nor-NOHA; L-Nor-NOHA; Arginase Inhibitor; 2-Amino-6-[(E)-(hydroxyimino)methyl]amino]hexanoic acid; BEC hydrochloride (related compound)
EINECS	Contact for details

Quality Control

Every batch of Argadin is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity, chiral purity, and impurity profiles. Our quality commitment supports compliance with research and development standards, ensuring reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% (L-Isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.