Description

2-Aminopyrimidine-5-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a key synthetic intermediate. This compound is valued for its role in constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce sulfonamide or sulfonate functionalities into pyrimidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with specific electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Aminopyrimidine-5-Sulfonyl Chloride
CAS No.	289484-00-0
Molecular Formula	C4H4ClN3O2S
Molecular Weight	193.61 g/mol
Synonyms	5-(Chlorosulfonyl)pyrimidin-2-amine; 2-Amino-5-chlorosulfonylpyrimidine; Pyrimidine-5-sulfonyl chloride, 2-amino-; 2-Aminopyrimidine-5-sulfonyl chloride; 5-Chlorosulfonyl-2-pyrimidinamine; 2-Amino-5-pyrimidinesulfonyl chloride; 2-Pyrimidinamine, 5-(chlorosulfonyl)-
EINECS	Contact for details

Quality Control

Our 2-Aminopyrimidine-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.