Description

6-Aminopyridine-3-Sulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride and the aromatic amine—which enable its use as a key precursor for creating sulfonamides and other complex heterocyclic structures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzymes via sulfonamide-based inhibition.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require sulfonyl-containing bioactive cores.
• Material Science Research: Serves as a monomer or cross-linking agent for creating specialty polymers and functional materials with specific sulfonamide linkages.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling biomolecules or creating activity-based probes due to its electrophilic sulfonyl chloride group.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized azo dyes and colorants with enhanced properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a sulfonamide pharmacophore.

Basic Information

Product Name	6-Aminopyridine-3-Sulfonyl Chloride
CAS No.	289483-92-7
Molecular Formula	C5H5ClN2O2S
Molecular Weight	192.62 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 6-amino-; 6-Amino-3-pyridinesulfonyl chloride; 2-Amino-5-pyridinesulfonyl chloride; 5-Aminopyridine-2-sulfonyl chloride; 2-Aminopyridine-5-sulfonyl chloride; 6-Aminonicotinic acid sulfonyl chloride; 6-Aminopyridine-3-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Aminopyridine-3-Sulfonyl Chloride is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Soluble in common organic solvents (DMF, DMSO, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.