Description

2-Bromo-1-Fluoro-3,5-Dimethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine substituents on a dimethylbenzene scaffold, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of halogen atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal molecules for electronic displays and lighting applications.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for studying the effects of fluorine substitution on aromatic systems in academic and industrial R&D settings.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts used in asymmetric synthesis and polymerization processes.

Basic Information

Product Name	2-Bromo-1-Fluoro-3,5-Dimethylbenzene
CAS No.	289038-20-6
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-Bromo-2-fluoro-4,6-dimethylbenzene; 2-Fluoro-6-bromo-m-xylene; 3,5-Dimethyl-2-bromofluorobenzene; 2-Bromo-1-fluoro-3,5-dimethylbenzene; 2-Bromo-6-fluoro-1,3-dimethylbenzene; m-Xylene, 2-bromo-1-fluoro-; Benzene, 2-bromo-1-fluoro-3,5-dimethyl-
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-1-Fluoro-3,5-Dimethylbenzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (GC, HPLC, NMR) to verify identity and quantify impurities. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We operate under a quality system designed to meet the rigorous standards of our global B2B clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.